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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue " Vol 25, No 03 (1993)" : 7 Documents clear
Cytologic examination of the thoracocenthesis fluid for the diagnosis of a malignant mesothelioma and adenocarcinoma. A comparative diagnosis. Ahmad Ghozali, Ahmad Ghozali
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Reccurent pleural effusions are frequently the first manifestation of a diffuse malignant pleural mesothelioma. Pleural effusion of the malignant mesothelioma is frequently indistinguishable from the pleural effusion due to adenocarcinoma. The prognosis of this tumor is poor, but immediate and accurate therapy will render prolonged remission. For these reasons, microscopic examination of thoracocenthesis fluid is necessary, because it may provide an immediate diagnosis.Unfortunately, the reliability of cytologic diagnosis is still disputable. Based on microscopic examination, there is no single pathognomonic feature. The cytologic diagnosis of a malignant pleural examination is based on the constellation of findings. The history of the course of the disease, optimal sample preparation, and special stains are important requirements to provide definitive diagnosis.Key Words: mesothelioma adenocarcinoma thoracocenthesis fluid air-dried May Grunwald - Giemsa monoclonal antibody B72.3
Disproportional changes of glucose, lactic acid and haemoglobin level as parameters for physical performance test
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Levels of blood Hb, glucose and lactic acid were estimated two times to 49 athletes of badminton and tennis (13-27 years old). The estimations were done before and after physical performance test. The loads of physical performance test for the subjects were different to each other, depending on their capacities. The changes of Hb concentration were used to correct the changes of glucose and lactic acid concentrations due to the changes of blood volume. The Hb concentrations of 35 subjects increased and the rest of 14 decreased; they were called group A (n=35) and group B (n=14) respectively. When blood glucose concentrations were observed from group A, 24 of them decreased (group At) while the remaining 11 increased. After it had been adjusted to the changes of blood volume, the blood glucose concentration of 4 among the 11 persons (group A2) became lower, while the other 7 subjects remained high (group A3). Blood glucose concentrations of group B increased even after adjusted to the changes of blood volume. The lactic acid concentrations of all subjects also increased after adjusted to the changes of blood volume.Key words: athletes blood haemoglobin glucose lactic acid physical performance
Role of insulin resistance and hyperinsulinemia in cardiovascular disease Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Resi,stance to insulin-stimulated glucose uptake is present in the great majority of patients with impaired glucose tolerance or type 2 diabetes mellitus, in first degree relatives of patients with type 2 diabetes mellitus, as well as in approximately 25% of non-obese individuals with normal oral glucose tolerance. Deterioration of glucose tolerance can be prevented if beta cell is able to produce more insulin resulting hyperinsulinemia.The association between hypertension and diabetes mellitus is well recognized. Several reasons for the coexistence of these disorders have been postulated, i.e. as part of aging process, diabetes causes macrovascular and microvascular disease, renovascular stenosis which is enhanced by the development of hypertension. Insulin causes renal sodium reabsorption, stimulates the sympathetic nervous system, increases intracellular calcium, and is a vascular growth factor.Insulin resistance, hyperinsulinemia, impaired glucose tolerance, increased plasma triglyceride, and decreased HDL-cholesterol concentration have been shown to be associated with increased risk of coronary heart disease. Based upon these considerations, it raised the possibility that insulin resistance and hyperinsulinemia are involved in the etiology and clinical course of three major related disease; the type 2 diabetes mellitus, hypertension, and coronary heart disease.Key Words: hyperinsulinemia insulin resistance cardiovascular disease glucose homeostasis aging
Hepatitis-C virus (HCV) Suwarso, Suwarso
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A new problem on hepatitis for Indonesian is hepatitis-C virus (HCV). This infection is endemic, majority sub-clinic and progressive in chronic. Viral transmission is primarily via a parenteral route, while other routes are still in debate.Diagnostic approach should be focused on how this virus developed.KeyWords: hepatitis-C virus molecular biology Westem-blot-HCV blood transfusion epidemiology
Usia Lanjut Anonim, Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Key Words: Ageing
The new concepts in basic oncology research Soeripto, Soeripto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Research on epidemiology, pathology, clinical course, and treatment of cancer is available. The epidemiological and clinical research on cancer must be brought into a comprehensive scheme. Basic research on oncology is suggested to be based on cancer epidemiology, and applicable for clinical practice. This article discusses the new concept of basic oncology research using breast cancer as a model.It is concluded that the new concepts in basic oncology research have to be based on the community need. It will be better if the research is multidisciplinary and multiinstitutional approach. Using this approach the expectation is that and the result could solve the problem either in the community or in the hospital.Key Words: oncology-cancer epidemiology-breast cancer oncogen-immunohistoclinical signs -prognostic index
The Use of Monoclonal Antibody in the Detection of Circulating Antigen in Malayan Filariasis Cases: a Preliminary Report Soeyoko, Soeyoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Filariasis (penyakit kaki gajah) di Indonesia disebabkan oleh cacing filaria. Wuchereria bancrofti, Brugia malayi dan Brugia tintori. Dan ketiga spesies tersebut, B. malayi merupakan penyebab utama filariasis terutama di daerah endemik di luar Jawa. Diagnosis filariasis sampai saat ini masih didasarkan atas hasil pemeriksaan klinis, parasitologis dan imunologis konvensional, namun ketiga cara tersebut banyak kelemahannya.Dalam era bioteknologi, dengan diternukannya teknik hibridoma; dapat dihasilkan antibodi monoklonal yang spesifik terhadap filaria B. malayi dan mampu mengikat circulating antigen dalam senim penderita filariasis.Dengan teknik pemeriksaan dot-blot didapatkan serum yang mengandung circulating antigen sebagai berikut: 75% pada serum kelompok penderita simtomatik-rnikrofilarernia; 40% serum kelompok penderita shntomatik-amikrofilaremia; 88,8% serum kelompok penderita asimtomatik-mikrofilarernia; dan 19,6% serum kelompok penderita asimtomatik-amikrofdarentia.Antibodi monoklonal dapat membantu diagnosis filariasis terutama pada yang asimtomat ik-amikrofilarem ia.Key Words: Brugia malayi- filariasis-filarial circulating antigen-antifilarial monoclonal antibodies-dot-blot assay

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